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  • How Does Praziquantel Work as an Antiparasitic? – Medzsupplier

    Posted by James James on July 4, 2024 at 9:35 pm

    Praziquantel is a commonly used Antiparasitic drug that works well against many different types of parasitic worms, but especially well against flukes (trematodes) and tapeworms (cestodes). Its main utility is in treating infections brought on by these parasites in both human and veterinary medicine.

    Praziquantel works by compromising the integrity of the parasite’s cell membrane. Praziquantel enters the bloodstream quickly after administration and travels to the parasite target. It makes the parasite’s cell walls more permeable to calcium ions. The parasite becomes paralyzed as a result of the strong muscle contractions brought on by this calcium surge. The parasite cannot continue to attach itself to the intestinal wall or other tissue of the host due to the ensuing paralysis of the muscles.

    Furthermore, the parasite’s tegument, or outer surface, is severely damaged by praziquantel, leaving it vulnerable to the host’s immune system and digestive enzymes. This causes the parasite to break down and be expelled by the host’s body through natural elimination mechanisms.

    Praziquantel’s safety profile and broad-spectrum efficacy are well rated. It comes in a number of forms, including as pills and injectable solutions, and is usually taken orally. The medication has few side effects and is quickly digested and removed, making it appropriate for usage in a variety of patients, including those with weakened immune systems.

    In conclusion, praziquantel is a strong Antiparasitic that kills parasites by causing Tegumental damage and muscular paralysis, which causes the parasites to die and be removed from the host. It is a mainstay in the treatment of parasitic infections due to its safety and efficacy.

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    James James replied 2 months ago 1 Member · 0 Replies
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